Jamun herb Eugenia jambolana plant medicinal properties

Jamun seed has gastro-protective properties mainly through promotion of mucosal defensive factors and antioxidant status and decreasing lipid peroxidation. Jamun also has anti cancer and anti viral potential.

Jamun fruit extract and breast cancer
Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells.
J Agric Food Chem. 2009 February. Li L, Adams LS, Chen S, Killian C, Ahmed A, Seeram NP. Department of Biomedical and Pharmaceutical Sciences, Bioactive Botanical Research Laboratory, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island, USA.
The ripe purple berries of the native Indian plant Eugenia jambolana Lam., known as Jamun, are popularly consumed and available in the United States in Florida and Hawaii. Despite the growing body of data on the chemopreventive potential of edible berry extracts, there is paucity of such data for Jamun fruit. Therefore our laboratory initiated the current study with the following objectives: to prepare a standardized Jamun fruit extract for biological studies and to investigate the antiproliferative and pro-apoptotic effects of Jamun fruit extract in estrogen dependent/aromatase positive (MCF-7aro), and estrogen independent (MDA-MB-231) breast cancer cells, and in a normal/nontumorigenic (MCF-10A) breast cell line. Jamun fruit extract was standardized to anthocyanin content 3.5% anthocyanins (as cyanidin-3-glucoside equivalents) which occur as diglucosides of five anthocyanidins / aglycons: delphinidin, cyanidin, petunidin, peonidin and malvidin. In the proliferation assay, Our studies suggest that Jamun fruit extract may have potential beneficial effects against breast cancer.

Jamun has antiviral activity
In vitro antiviral activity of plant extracts on goatpox virus replication.
Indian J Exp Biol. 2008 Feb; Bhanuprakash V, Hosamani M, Balamurugan V, Gandhale P, Naresh R, Swarup D, Singh RK. Division of Virology, Indian Veterinary Research Institute, Mukteswar 263 138, India.
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana ( Jamun ) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Results indicated that the extract of Acacia arabica and Jamun leaves inhibited GTPV replication in vitro.

Liver health
Hepatoprotective activity of Eugenia jambolana Lam. in carbon tetrachloride treated rats.
Indian J Pharmacol. 2009 Feb; Sisodia SS, Bhatnagar M. Department of Pharmacology, Bhupal Nobles' Girls College of Pharmacy, Udaipur, Rajasthan, India.
To estimate the hepatoprotective effects of the methanolic seed extract of Eugenia jambolana Lam. (Myrtaceae), in Wistar albino rats treated with carbon tetrachloride (CCl(4)). Liver damage in rats treated with CCl(4) administered subcutaneously, on alternate days for one week) was studied by assessing parameters such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), acid phosphatase (ACP) and bilirubin (total and direct). The effect of co-administration of Eugenia jambolana Lam on the above parameters was investigated. These biochemical observations were supplemented by weight and histological examination of liver sections. Liv.52((R)) was used as positive control. Data were analyzed by one way ANOVA, followed by Scheff's/Dunnett's test. Administration of Eugenia jambolana Lam. significantly prevented carbon tetrachloride induced elevation of serum SGOT, SGPT, ALP, ACP and bilirubin (total and direct) level. Histological examination of the liver section revealed hepatic regeneration, after administration of various doses of Eugenia jambolana Lam. The results were comparable to that of Liv.52). The study suggests preventive action of Jamun in carbon tetrachloride induced liver toxicity. Hepatic cell regeneration process was dose dependent.

Insomnia cures herbs for sleep